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pentobarbital will lessen the level or impact of diazepam intranasal by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Observe. Strong or average CYP3A4 inducers might enhance charge of diazepam elimination; therefore, efficacy of diazepam might be reduced.pentobarbital will lower the level or outcome of lonafarnib by impacting